Eriksen did indeed make the difference. As mentioned above, Lamela or Lucas could have also been substituted instead of Winks, that wasn't the issue.
Winks played well but I don't think it was smart to make him, effectively, playmaker - he doesn't have the tools to play that role - his balls out to the full-backs were looping and slow - it's just not his thing, and I think that was a big mistake from Pochettino. Either Lamela or Lucas should have been given the role, in the absence of Eriksen.
The mistake, as always, was playing a diamond without the personnel to do so.
Winks was fine. Arguably our best player whilst he was on the pitch along with KWP.
Lamela and Lucas however were dreadful. Especially until we changed to a 4231 which is the formation we should be playing all the time if we aren't going with a 433.
And Winks should then be starting everytime alongside Ndombele.