Even playing those 3 up front, and with Bergwijn and Moura looking knackered this evening, I think you will find Dele and maybe Sessegnon on in the 2nd half for them.
My assessment of Ndomebele's ability to last more than 45 minutes doesn't change, so only question is who comes on for him probably after 45 mins - Gedson who on his debut was probably the least influential player this evening, Dier with all the flaws we know or Skipp who has hardly played this season. No easy choices ?
You'd just bring on Dele after 60 minutes and play him in front of Winks/Lo Celso who were exceptional against City together.